Occams will be represented at WCoP 2016 in Brisbane by Rik Schoemaker. Meet him there or come see his poster on nlmixr: an open-source package for pharmacometric modelling in R on Monday, 22 August, 2016, 12.15-1:15 pm. nlmixr is a highly exciting open-source development that allows non-linear mixed effect modelling using R and the nlme package, but implementing full dosing flexibility along with ordinary differential equations, and computational speed by compling to C. A live demo will be possible, so come see Rik if you are interested!
At Occams we believe in providing academic output next to our consultancy work, and we are therefore happy to announce that we have co-authored two publications over the last months:
- Peter L. Bonate, Malidi Ahamadi, Nageshwar Budha, Amparo de la Peña, Justin C. Earp, Ying Hong, Mats O. Karlsson, Patanjali Ravva, Ana Ruiz-Garcia, Herbert Struemper, and Janet R. Wade. Methods and strategies for assessing uncontrolled drug–drug interactions in population pharmacokinetic analyses: results from the International Society of Pharmacometrics (ISOP) Working Group. J Pharmacokinet Pharmacodyn (2016) 43: 123.
- Rik Schoemaker, Janet R. Wade, and Armel Stockis. Brivaracetam Population Pharmacokinetics and Exposure-Response Modeling in Adult Subjects With Partial-Onset Seizures. Journal of Clinical Pharmacology (2016). doi: 10.1002/jcph.761.
We are extremely proud and honoured that Occams is has been granted two oral presentations at PAGE 2016! One will be presented by Lutz Harnisch (Pfizer) in a collaborative project with Pharmetheus, Occams and Pfizer with the title Modelling and simulation of neurological endpoints (modified Rankin Scale [mRS] and National Institute of Health Stroke Scale [NIHSS]) to aid clinical trial design in intracerebral hemorrhage (ICH), and one will be presented by Rik Schoemaker (Occams) with the title Extrapolation of a Brivaracetam Exposure-Response Model from Adults to Children on work performed while at Exprimo in collaboration with UCB.
Occams is committed to supporting global training, research and development in the field of pharmacometrics. Our consultants are variously associated with PAGE and the International Society of Pharmacometrics (ISoP), and in 2016 we are proud to be sponsors of PAGE (www.page-meeting.org), WCoP (wcop2016.org) and PMX Benelux !
Occams will be represented at ACoP 2015 by Rik Schoemaker. Meet him there or come see his poster (T-50) on Modeling the Effect of Levetiracetam on Daily and Aggregated Seizure Counts in Adults and Children on Tuesday, October 6, 2015, 7.30-9.00 am.